Evolution of Ferripyoverdine Receptors in Pseudomonas Aeruginosa


Non-Fiction - Education
156 Pages
Reviewed on 08/07/2014
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Author Biography

Osayande Osaretin Julie was born July 15, 1976 in Benin City, Nigeria, she studied Biochemistry at the University of Benin, Benin City, Nigeria where she graduated with second class honors, upper division, she obtained a Master's in Molecular Biology at the Free University Brussels, in Belgium thereafter, she obtained a scholarship to pursue a PhD degree at the same University.

    Book Review

Reviewed by Jack Magnus for Readers' Favorite

Evolution of Ferripyoverdine Receptors in Pseudomonas Aeruginosa is a scientific work written by Julie Osaretin Osayande, a molecular biologist. Pseudomonas Aeruginosa is a type of bacteria that occurs in nature as well as in hospitals, where it attacks patients who have compromised immune systems. This bacteria is able to evolve to adapt to new or challenging environments and has become resistant to many antibiotics. Osayande studied the reactions of both wild P. Aeruginosa, found in a river in Brussels, and that found in a Brussels hospital to see how its Ferripyoverdine Receptors evolve to survive. Ferripyoverdine Receptors are used by P. Aeruginosa to chelate the iron it needs for metabolic functioning. P. Aeruginosa is a virulent bacterium that affects many cystic fibrosis patients, as well as burn victims and cancer patients. This ubiquitous bacterium has even been linked to eye infections caused by contact lens use. Osayande’s studies are designed to determine if antibiotic-resistant P. Aeruginosa can be fooled into accepting iron compounds that have been doctored to include antibiotics.

Julie Osaretin Osayande’s scientific work, Review of Evolution of Ferripyoverdine Receptors in Pseudomonas Aeruginosa, is a fascinating look into the world of molecular biology. Osayande presents her subject in a way that makes it relatively accessible to the layman. While her topic was totally new to me, with a bit of effort I was able to follow along as she presented her propositions, discussions and study data. In the process, I learned a lot about molecular biology and the advances scientists are making in their efforts to combat antibiotic-resistant organisms. Osayande also discussed how researchers studying the HIV virus are researching how to adapt certain properties that virus uses to attack cells to utilize them to attack P. Aeruginosa. Each chapter in this work has an introduction that sets out its main theme and is concluded with an extensive reference list. Evolution of Ferripyoverdine Receptors in Pseudomonas Aeruginosa is not necessarily written with the non-scientist in mind, but it’s a highly accessible treatise that is well worth reading.